Epithalon Product Description
Epithalon is a short synthetic peptide built from four amino acids in the sequence Ala-Glu-Asp-Gly. Its structure was modeled on the amino acid composition of Epithalamin, a pineal gland extract studied in gerontology research.
As a defined tetrapeptide, Epithalon is well suited to analytical and mechanistic work. It is supplied as a filler-free lyophilized powder and reconstituted with a sterile solvent immediately before experimental use.
The compound sits within the pineal and AEDG peptide research area, alongside related bioregulator compounds studied for cellular signaling and regulatory function.
Compound Specifications
| Property |
Value |
| CAS Number |
307297-39-8 |
| PubChem CID |
219042 |
| Molecular Formula |
C₁₄H₂₂N₄O₉ |
| Molecular Weight |
390.35 g/mol |
| Amino Acid Sequence |
Ala-Glu-Asp-Gly (AEDG) |
| Sequence Length |
4 residues (tetrapeptide) |
| IUPAC |
L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-glycine |
| Synonyms |
Epitalon, Epithalamin, AEDG peptide |
| Source |
Synthetic |
| Purity |
≥99% (HPLC) |
| Appearance |
Lyophilized white powder |
| Solubility |
Soluble in water |
| Storage |
-20°C, protect from light |
Epithalon Peptide Structure

Source: PubChem
Research Applications
| Research Area |
In Vitro Application |
| Telomere biology |
Experimental systems measuring telomerase-associated activity and telomere-length metrics in cell-based models |
| Gene expression |
Assays quantifying transcriptional changes in defined differentiation markers |
| Epigenetic regulation |
Molecular-modeling and binding studies of peptide and histone interactions |
| Peptide characterization |
Analytical evaluation of tetrapeptide identity, sequence, and stability |
Storage and Handling
- Store the lyophilized compound at -20°C, protected from light.
- After reconstitution, store at 2-8°C and use promptly.
- Maintain aseptic handling to preserve compound integrity.
Certificate of Analysis (COA) for Every Batch
A Certificate of Analysis (COA) is a document that verifies a compound’s identity, purity, and batch quality through independent laboratory testing. Every compound from BioLongevity Labs ships with a COA tied to its specific batch, so researchers can confirm exactly what they received before it enters a protocol.
Each COA reports results from third-party laboratory analysis, including:
- Ultra-high-performance liquid chromatography with mass spectrometry (UHPLC-MS) for purity, typically confirmed at 99% or higher
- Mass identification for molecular confirmation and content quantitation
- Endotoxin quantitation by Limulus amebocyte lysate (LAL) assay where applicable
- Visual and physical characterization of the finished material
How to verify a COA independently
Every certificate can be checked against the issuing laboratory’s own records, not just the copy hosted here. Verification does not depend on BioLongevity Labs.
- MDx BioAnalytical Laboratory certificates carry a QC tracking number and a search code. Newer certificates also carry a QR code. Scan the code, or enter the search code at mdxbiolabs.com, to pull the official record.
- BioRegen reports of analysis carry a Report ID and a Validation Key. Scan the QR code on the certificate to open the official record, or reference both identifiers when contacting the laboratory at the address printed on the report.
- SafeCert Labs certificates, which appear on a number of earlier batches, carry a COA number and the signature of the reporting chemist. Reference that number when requesting confirmation from the laboratory directly.
Batches are frequently tested by both laboratories independently. When two certificates exist for the same lot, each one resolves at its own issuing laboratory, which lets a researcher confirm the same material twice through two unrelated sources.
COAs are sourced from independent certified labs rather than in-house testing alone, giving researchers a verifiable record of molecular integrity for each batch. All compounds are supplied for research use only.
Review the COAs for this batch below, or browse the full COA library.
Epithalon (261474)

Epithalon (260821)

Epithalon (12097)

Epithalon (260259)

Ephitalon(10920)

Epithalon (2502050023)

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